Characterization of drug-release kinetics in trabecular bone from titania nanotube implants | Zendy

Dušan Lošić | Zendy; Gerald J. Atkins | Zendy; Peter Pivonka | Zendy; David Findlay | Zendy; Moom Sinn Aw | Zendy; Kamarul Ariffin Khalid | Zendy; Karan Gulati | Zendy

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Characterization of drug-release kinetics in trabecular bone from titania nanotube implants

Author(s) -

Dušan Lošić,

Gerald J. Atkins,

Peter Pivonka,

David Findlay,

Moom Sinn Aw,

Kamarul Ariffin Khalid,

Karan Gulati

Publication year - 2012

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s33655

Subject(s) - drug delivery , biomedical engineering , materials science , ex vivo , cancellous bone , femoral canal , biocompatibility , trabecular bone , implant , dentistry , nanotechnology , chemistry , medicine , surgery , in vitro , prosthesis , pathology , biochemistry , osteoporosis , metallurgy

The aim of this study was to investigate the application of the three-dimensional bone bioreactor for studying drug-release kinetics and distribution of drugs in the ex vivo cancellous bone environment, and to demonstrate the application of nanoengineered titanium (Ti) wires generated with titania nanotube (TNT) arrays as drug-releasing implants for local drug delivery

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