Carbon nanotube interaction with extracellular matrix proteins producing scaffolds for tissue engineering
Author(s) -
Rodrigo R. Resende,
Fernanda Maria Policarpo Tonelli,
Anderson K. Santos,
Kátia N. Gomes,
Eudes Lorençon,
Luiz O. Ladeira,
Sílvia Guatimosim
Publication year - 2012
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s33612
Subject(s) - biocompatibility , carbon nanotube , extracellular matrix , materials science , tissue engineering , scaffold , carbon nanotube metal matrix composites , biomedical engineering , regeneration (biology) , nanotechnology , transplantation , biodegradation , nanotube , chemistry , surgery , medicine , microbiology and biotechnology , organic chemistry , biochemistry , metallurgy , biology
In recent years, significant progress has been made in organ transplantation, surgical reconstruction, and the use of artificial prostheses to treat the loss or failure of an organ or bone tissue. In recent years, considerable attention has been given to carbon nanotubes and collagen composite materials and their applications in the field of tissue engineering due to their minimal foreign-body reactions, an intrinsic antibacterial nature, biocompatibility, biodegradability, and the ability to be molded into various geometries and forms such as porous structures, suitable for cell ingrowth, proliferation, and differentiation. Recently, grafted collagen and some other natural and synthetic polymers with carbon nanotubes have been incorporated to increase the mechanical strength of these composites. Carbon nanotube composites are thus emerging as potential materials for artificial bone and bone regeneration in tissue engineering.
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