Open AccessImproved pharmacokinetics and reduced toxicity of brucine after encapsulation into stealth liposomes: role of phosphatidylcholine
Author(s) -
Chen,
Yan Yan,
Hu,
Gu
Publication year - 2012
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s32860
Subject(s) - brucine , calcein , liposome , phosphatidylcholine , pharmacokinetics , chemistry , chromatography , pharmacology , zeta potential , biochemistry , medicine , materials science , membrane , phospholipid , nanotechnology , nanoparticle , strychnine
Brucine was encapsulated into stealth liposomes using the ammonium sulfate gradient method to improve therapeutic index.
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