Lipid-based liquid crystalline nanoparticles as oral drug delivery vehicles for poorly water-soluble drugs: cellular interaction and in vivo absorption
Author(s) -
Jun Chen,
Zeng,
Gao,
Hu,
Song,
Xia,
Liu,
Gu,
Zhiqing Pang,
Chen Chen,
Fang Fang Fang Fang
Publication year - 2012
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s32599
Subject(s) - in vivo , drug delivery , absorption (acoustics) , nanoparticle , drug , materials science , nanotechnology , drug carrier , pharmacology , medicine , microbiology and biotechnology , biology , composite material
Lipid-based liquid crystalline nanoparticles (LCNPs) have attracted growing interest as novel drug-delivery systems for improving the bioavailability of both hydrophilic and hydrophobic drugs. However, their cellular interaction and in vivo behavior have not been fully developed and characterized.
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