Core-shell hybrid liposomal vesicles loaded with panax notoginsenoside: preparation, characterization and protective effects on global cerebral ischemia/reperfusion injury and acute myocardial ischemia in rats
Author(s) -
Jing Zhang,
Zhang Zhang,
Xiang Li,
Zhao,
Luo,
Wei-San Pan,
Liao
Publication year - 2012
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s32385
Subject(s) - in vivo , pharmacology , liposome , ischemia , lactate dehydrogenase , neuroprotection , medicine , chemistry , biochemistry , biology , enzyme , microbiology and biotechnology
Novel panax notoginsenoside-loaded core-shell hybrid liposomal vesicles (PNS-HLV) were developed to resolve the restricted bioavailability of PNS and to enhance its protective effects in vivo on oral administration.
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