Open AccessSelf-assembled mPEG–PCL-g–PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro
Author(s) -
Zhiyong Qian
Publication year - 2012
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s28932
Subject(s) - in vitro , micelle , dna , materials science , chemistry , combinatorial chemistry , biochemistry , organic chemistry , aqueous solution
In this paper, a series of amphiphilic triblock copolymers based on polyethylene glycol-poly ɛ-caprolactone-polyethylenimine (mPEG-PCL-g-PEI) were successfully synthesized, and their application for codelivery of chemotherapeutic drugs and DNA simultaneously was investigated.
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