z-logo
open-access-imgOpen Access
Titanium dioxide induces apoptotic cell death through reactive oxygen species-mediated Fas upregulation and Bax activation
Author(s) -
SuJae Lee,
Yoo,
Yoon Yoon,
Kwon,
Hyun,
Woo,
Kim,
Lim,
Suh
Publication year - 2012
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s28647
Subject(s) - downregulation and upregulation , reactive oxygen species , apoptosis , microbiology and biotechnology , programmed cell death , titanium dioxide , oxygen , materials science , biophysics , chemistry , biology , biochemistry , gene , organic chemistry , metallurgy
Titanium dioxide (TiO(2)) has been widely used in many areas, including biomedicine, cosmetics, and environmental engineering. Recently, it has become evident that some TiO(2) particles have a considerable cytotoxic effect in normal human cells. However, the molecular basis for the cytotoxicity of TiO(2) has yet to be defined.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom