Celastrol nanoparticles inhibit corneal neovascularization induced by suturing in rats | Zendy

Dan Liang | Zendy; Zhanrong Li | Zendy; Yao Lin | Zendy; Jingguo Li | Zendy; Zhang | Zendy; Xianghua Wu | Zendy; Yi Liu | Zendy; Miaoli Lin | Zendy; Wenru Su | Zendy; Yongping Li | Zendy

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Celastrol nanoparticles inhibit corneal neovascularization induced by suturing in rats

Author(s) -

Dan Liang,

Zhanrong Li,

Yao Lin,

Jingguo Li,

Zhang,

Xianghua Wu,

Yi Liu,

Miaoli Lin,

Wenru Su,

Yongping Li

Publication year - 2012

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s27860

Subject(s) - celastrol , corneal neovascularization , chemistry , angiogenesis , umbilical vein , cornea , vascular endothelial growth factor , neovascularization , microbiology and biotechnology , biophysics , materials science , biochemistry , medicine , in vitro , apoptosis , biology , cancer research , ophthalmology , vegf receptors

Celastrol, a traditional Chinese medicine, is widely used in anti-inflammation and anti-angiogenesis research. However, the poor water solubility of celastrol restricts its further application. This paper aims to study the effect of celastrol nanoparticles (CNPs) on corneal neovascularization (CNV) and determine the possible mechanism.

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