Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder cancer | Zendy

Tzu yin Lin | Zendy; Hongyong Zhang | Zendy; Juntao Luo | Zendy; Yuanpei Li | Zendy; Tingjuan Gao | Zendy; Primo N. Lara | Zendy; Ralph de Vere White | Zendy; Kit S. Lam | Zendy; Chong Xian Pan | Zendy

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Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder cancer

Author(s) -

Tzu yin Lin,

Hongyong Zhang,

Juntao Luo,

Yuanpei Li,

Tingjuan Gao,

Primo N. Lara,

Ralph de Vere White,

Kit S. Lam,

Chong Xian Pan

Publication year - 2012

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s27734

Subject(s) - nanocarriers , micelle , in vivo , bladder cancer , drug delivery , paclitaxel , targeted drug delivery , cancer cell , pharmacology , drug carrier , cancer research , cancer , drug , medicine , chemistry , biophysics , materials science , nanotechnology , biology , aqueous solution , microbiology and biotechnology

We previously developed a bladder cancer-specific ligand (PLZ4) that can specifically bind to both human and dog bladder cancer cells in vitro and in vivo. We have also developed a micelle nanocarrier drug-delivery system. Here, we assessed whether the targeting micelles decorated with PLZ4 on the surface could specifically target dog bladder cancer cells.

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