Synthesis, characterization, and in vivo efficacy evaluation of PGG&ndash;docetaxel conjugate for potential cancer chemotherapy | Zendy

Sang Van | Zendy; Yang | Zendy; Shu | Zendy; Danbo Yang | Zendy; Ge Ge | Zendy; Xinguo Jiang | Zendy; Jin Jin | Zendy; Lei Yu | Zendy

Open Access

Synthesis, characterization, and in vivo efficacy evaluation of PGG–docetaxel conjugate for potential cancer chemotherapy

Author(s) -

Sang Van,

Yang,

Shu,

Danbo Yang,

Ge Ge,

Xinguo Jiang,

Jin Jin,

Lei Yu

Publication year - 2012

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s26842

Subject(s) - conjugate , in vivo , cytotoxicity , dynamic light scattering , biophysics , chemistry , bioavailability , docetaxel , materials science , particle size , in vitro , nanoparticle , biochemistry , nanotechnology , pharmacology , biology , chemotherapy , genetics , mathematical analysis , mathematics , microbiology and biotechnology

This work is intended to develop and evaluate a biopolymeric poly(L-γ-glutamylglutamine) (PGG)-docetaxel (DTX) conjugate that can spontaneously self-assemble in aqueous solutions to become nanoparticles.

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