Perorally active nanomicellar formulation of quercetin in the treatment of lung cancer | Zendy

Gigi N.C. Chiu | Zendy; Tan | Zendy; Liu | Zendy; Chang | Zendy; Lim | Zendy

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Perorally active nanomicellar formulation of quercetin in the treatment of lung cancer

Author(s) -

Gigi N.C. Chiu,

Tan,

Liu,

Chang,

Lim

Publication year - 2012

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s26538

Subject(s) - quercetin , micelle , chemistry , polyethylene glycol , bioavailability , peg ratio , dispersity , solubility , pharmacology , aqueous solution , biochemistry , organic chemistry , medicine , finance , economics , antioxidant

Realizing the therapeutic benefits of quercetin is mostly hampered by its low water solubility and poor absorption. In light of the advantages of nanovehicles in the delivery of flavanoids, we aimed to deliver quercetin perorally with nanomicelles made from the diblock copolymer, polyethylene glycol (PEG)-derivatized phosphatidylethanolamine (PE).

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