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Preventing postoperative abdominal adhesions in a rat model with PEG-PCL-PEG hydrogel
Author(s) -
Zhiyong Qian,
Yang� Yang,
Changyang Gong,
Zhao,
Zhou,
Li,
Qi,
Zhong,
Luo
Publication year - 2012
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s26141
Subject(s) - ethylene glycol , adhesion , peg ratio , self healing hydrogels , tissue adhesion , biocompatible material , peritoneum , fibroblast , cell adhesion , medicine , surgery , biomedical engineering , chemistry , in vitro , polymer chemistry , biochemistry , organic chemistry , finance , economics
Poly (ethylene glycol)-poly (ɛ-caprolactone)-poly (ethylene glycol) (PEG-PCL-PEG, PECE) hydrogel has been demonstrated to be biocompatible and thermosensitive. In this study, its potential efficacy and mechanisms of preventing postsurgical abdominal adhesions were investigated.

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