The efficacy of mitochondrial targeting antiresistant epirubicin liposomes in treating resistant leukemia in animals | Zendy

Ying Men | Zendy; Xiao-Xing Wang | Zendy; RuoJing Li | Zendy; Yan Zhang | Zendy; Wei Tian | Zendy; Hong-Juan Yao | Zendy; Rui-Jun Ju | Zendy; Xue Ying | Zendy; Jia Zhou | Zendy; Nan Li | Zendy; Liang Zhang | Zendy; Yang Yu | Zendy; WanLiang Lu | Zendy

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The efficacy of mitochondrial targeting antiresistant epirubicin liposomes in treating resistant leukemia in animals

Author(s) -

Ying Men,

Xiao-Xing Wang,

RuoJing Li,

Yan Zhang,

Wei Tian,

Hong-Juan Yao,

Rui-Jun Ju,

Xue Ying,

Jia Zhou,

Nan Li,

Liang Zhang,

Yang Yu,

WanLiang Lu

Publication year - 2011

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s24847

Subject(s) - epirubicin , k562 cells , apoptosis , pharmacology , leukemia , mitochondrion , cancer research , liposome , caspase 3 , multiple drug resistance , tunel assay , biology , programmed cell death , medicine , chemistry , immunology , cancer , drug resistance , biochemistry , breast cancer , microbiology and biotechnology

Multidrug resistance (MDR) of cancers can be circumvented by inducing programmed cell death, which is known as apoptosis. Mitochondria play a crucial role in apoptosis. Mitochondria-specific therapy would provide an efficient strategy for treating resistant cancers.

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