Electrospun PGA/gelatin nanofibrous scaffolds and their potential application in vascular tissue engineering | Zendy

Hadi Hajiali | Zendy; Shahgasempour | Zendy; Mohammad Reza NaimiJamal | Zendy; Peirovi | Zendy

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Electrospun PGA/gelatin nanofibrous scaffolds and their potential application in vascular tissue engineering

Author(s) -

Hadi Hajiali,

Shahgasempour,

Mohammad Reza NaimiJamal,

Peirovi

Publication year - 2011

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s24312

Subject(s) - gelatin , tissue engineering , differential scanning calorimetry , materials science , biocompatibility , fourier transform infrared spectroscopy , biomedical engineering , scaffold , scanning electron microscope , chemical engineering , composite material , chemistry , medicine , biochemistry , physics , metallurgy , thermodynamics , engineering

In this study, gelatin was blended with polyglycolic acid (PGA) at different ratios (0, 10, 30, and 50 wt%) and electrospun. The morphology and structure of the scaffolds were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, and differential scanning calorimetry. The mechanical properties were also measured by the tensile test. Furthermore, for biocompatibility assessment, human umbilical vein endothelial cells and human umbilical artery smooth muscle cells were cultured on these scaffolds, and cell attachment and viability were evaluated.

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