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In vivo migration of dendritic cells labeled with synthetic superparamagnetic iron oxide
Author(s) -
Qingang Hu
Publication year - 2011
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s24307
Subject(s) - lymph , prussian blue , in vivo , dendritic cell , confocal , green fluorescent protein , superparamagnetism , materials science , biodistribution , chemistry , fluorescence lifetime imaging microscopy , confocal microscopy , biophysics , pathology , in vitro , fluorescence , microbiology and biotechnology , biology , medicine , immunology , antigen , biochemistry , geometry , quantum mechanics , magnetic field , electrochemistry , mathematics , magnetization , physics , electrode , gene
Successful treatment of cancer with dendritic cell tumor vaccine is highly dependent on how effectively the vaccine migrates into lymph nodes and activates T cells. In this study, a simple method was developed to trace migration of dendritic cells to lymph nodes.

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