Open AccessCyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application
Author(s) -
Weiping Ren
Publication year - 2011
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s23530
Subject(s) - erythromycin , cyclodextrin , chemistry , drug delivery , osteoblast , drug , osteoclast , cytotoxicity , antibiotics , inflammation , pharmacology , biochemistry , medicine , immunology , in vitro , organic chemistry
Erythromycin, a hydrophobic antibiotic used to treat infectious diseases, is now gaining attention because of its anti-inflammatory effects and ability to inhibit osteoclasts formation. The aim of this study was to explore a cyclodextrin-erythromycin (CD-EM) complex for sustained treatment of orthopedic inflammation.
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