Preparation, characterization, and efficient transfection of cationic liposomes and nanomagnetic cationic liposomes | Zendy

Saman Hosseinkhani | Zendy; Samadikhah | Zendy; Majidi | Zendy; Nikkhah | Zendy

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Preparation, characterization, and efficient transfection of cationic liposomes and nanomagnetic cationic liposomes

Author(s) -

Saman Hosseinkhani,

Samadikhah,

Majidi,

Nikkhah

Publication year - 2011

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s23074

Subject(s) - liposome , transfection , cationic liposome , lipofectamine , luciferase , gene delivery , in vivo , cationic polymerization , chinese hamster ovary cell , chemistry , microbiology and biotechnology , cytotoxicity , reporter gene , biophysics , in vitro , biochemistry , biology , gene expression , gene , vector (molecular biology) , recombinant dna , receptor , organic chemistry

Cationic liposomes (CLs) are composed of phospholipid bilayers. One of the most important applications of these particles is in drug and gene delivery. However, using CLs to deliver therapeutic nucleic acids and drugs to target organs has some problems, including low transfection efficiency in vivo. The aim of this study was to develop novel CLs containing magnetite to overcome the deficiencies.

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