Size-dependent in vivo toxicity of PEG-coated gold nanoparticles | Zendy

Xiaodong Zhang | Zendy; Wu | Zendy; Shen | Zendy; Liu | Zendy;  Sun | Zendy; Zhang | Zendy; Junpeng Fan | Zendy

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Size-dependent in vivo toxicity of PEG-coated gold nanoparticles

Author(s) -

Xiaodong Zhang,

Wu,

Shen,

Liu,

 Sun,

Zhang,

Junpeng Fan

Publication year - 2011

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s21657

Subject(s) - toxicity , in vivo , biodistribution , colloidal gold , spleen , nanoparticle , biophysics , nanotoxicology , materials science , white blood cell , peg ratio , chemistry , nanotechnology , biology , immunology , microbiology and biotechnology , organic chemistry , finance , economics

Gold nanoparticle toxicity research is currently leading towards the in vivo experiment. Most toxicology data show that the surface chemistry and physical dimensions of gold nanoparticles play an important role in toxicity. Here, we present the in vivo toxicity of 5, 10, 30, and 60 nm PEG-coated gold nanoparticles in mice.

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