Controlled drug delivery systems for cancer based on mesoporous silica nanoparticles | Zendy

Nerea Iturrioz-Rodríguez | Zendy; Miguel A. CorreaDuarte | Zendy; Mónica L. Fanárraga | Zendy

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<p>Controlled drug delivery systems for cancer based on mesoporous silica nanoparticles</p>

Author(s) -

Nerea Iturrioz-Rodríguez,

Miguel A. CorreaDuarte,

Mónica L. Fanárraga

Publication year - 2019

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s198848

Subject(s) - mesoporous silica , drug delivery , nanotechnology , biocompatibility , nanomaterials , biocompatible material , materials science , nanoparticle , drug carrier , targeted drug delivery , drug , cancer therapy , mesoporous material , cancer , chemistry , biomedical engineering , pharmacology , medicine , biochemistry , metallurgy , catalysis

The implementation of nanotechnology in medicine has opened new research horizons particularly in the field of therapeutic delivery. Mesoporous silica particles have emerged as biocompatible drug delivery systems with an enormous potential in the treatment of cancer among many other pathologies. In this review, we focus on the unique properties of these particles as chemotherapy delivery carriers. Here, we summarize the general characteristics of these nanomaterials – including their physicochemical properties and customizable surfaces – different stimuli that can be used to trigger targeted drug release, biocompatibility and finally, the drawbacks of these types of nanomaterials, highlighting some of the most important features of mesoporous silica nanoparticles in drug delivery.

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