Optimizing supercritical antisolvent process parameters to minimize the particle size of paracetamol nanoencapsulated in L-polylactide | Zendy

Mahshid Kalani | Zendy; Yunus | Zendy; Abdullah | Zendy

Open Access

Optimizing supercritical antisolvent process parameters to minimize the particle size of paracetamol nanoencapsulated in L-polylactide

Author(s) -

Mahshid Kalani,

Yunus,

Abdullah

Publication year - 2011

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s18979

Subject(s) - supercritical fluid , materials science , particle size , process (computing) , particle (ecology) , chemical engineering , process engineering , nanotechnology , chromatography , chemistry , computer science , organic chemistry , engineering , operating system , oceanography , geology

The aim of this study was to optimize the different process parameters including pressure, temperature, and polymer concentration, to produce fine small spherical particles with a narrow particle size distribution using a supercritical antisolvent method for drug encapsulation. The interaction between different process parameters was also investigated.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research