Magnetic nanoparticles for gene and drug delivery
Author(s) -
Jon Dobson
Publication year - 2008
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s1608
Subject(s) - magnetic nanoparticles , drug delivery , drug , nanotechnology , targeted drug delivery , nanoparticle , gene delivery , materials science , nanomedicine , pharmacology , medicine , genetic enhancement , chemistry , gene , biochemistry
Investigations of magnetic micro- and nanoparticles for targeted drug delivery began over 30 years ago. Since that time, major progress has been made in particle design and synthesis techniques, however, very few clinical trials have taken place. Here we review advances in magnetic nanoparticle design, in vitro and animal experiments with magnetic nanoparticle-based drug and gene delivery, and clinical trials of drug targeting.
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