Open AccessmiR-221 suppression through nanoparticle-based miRNA delivery system for hepatocellular carcinoma therapy and its diagnosis as a potential biomarker
Author(s) -
Feng Li,
Feiran Wang,
Changlai Zhu,
Qun Wei,
Tianyi Zhang,
You Zhou
Publication year - 2018
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s157805
Subject(s) - hepatocellular carcinoma , microrna , in vivo , cancer research , biomarker , medicine , downregulation and upregulation , cancer , oncology , biology , biochemistry , microbiology and biotechnology , gene
MicroRNA-221(miR-221) is frequently dysregulated in cancer. The purpose of this study was to explore whether miR-221 can be used as a potential diagnostic marker or therapeutic target for hepatocellular carcinoma (HCC).
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