Thermoreversible Pluronic&reg; F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release, cell cytotoxicity, and uptake studies | Zendy

Zhijun Yang | Zendy; Shufang Nie | Zendy; W.L. Wendy Hsiao | Zendy; Weisan Pam | Zendy

Open Access

Thermoreversible Pluronic® F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release, cell cytotoxicity, and uptake studies

Author(s) -

Zhijun Yang,

Shufang Nie,

W.L. Wendy Hsiao,

Weisan Pam

Publication year - 2011

Publication title -

international journal of nanomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.245

H-Index - 128

eISSN - 1178-2013

pISSN - 1176-9114

DOI - 10.2147/ijn.s15057

Subject(s) - poloxamer , liposome , dialysis tubing , chromatography , differential scanning calorimetry , drug delivery , chemistry , materials science , biophysics , membrane , biochemistry , organic chemistry , copolymer , polymer , thermodynamics , physics , biology

To develop an in situ gel system comprising liposome-containing paclitaxel (PTX) dispersed within the thermoreversible gel (Pluronic® F127 gel) for controlled release and improved antitumor drug efficiency.

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