Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity
Author(s) -
Kayo Masuko
Publication year - 2009
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s5495
Subject(s) - viscosupplementation , hyaluronic acid , medicine , inflammation , arthritis , immunology , inflammatory arthritis , osteoarthritis , pathology , intra articular , alternative medicine , anatomy
Hyaluronic acid (HA) has been widely used for viscosupplementation of diseased or aged articular joints. However, recent investigations have revealed the active anti-inflammatory or chondroprotective effect of HA, suggesting its potential role in attenuation of joint damage. In particular, interactions between HA and other inflammatory mediators are attracting interest. This review summarizes several aspects of recent investigations of the anti-inflammatory effects of HA in arthritis.
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