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Overlap syndrome has been introduced to the field of hepatology to describe the coexistence of two or more autoimmune hepatic conditions in the same individual. This is a rare clinical case of a patient diagnosed with primary biliary cirrhosis (PBC) who later developed primary sclerosing cholangitis (PSC). This is a unique case as no other cases with a similar pattern have been reported. Overlap syndrome does not include the coexistence of PBC and PSC as a distinctive syndrome so far.

Overlap of primary biliary cirrhosis and primary sclerosing cholangitis &ndash; a rare coincidence or a new syndrome

Overlap of primary biliary cirrhosis and primary sclerosing cholangitis – a rare coincidence or a new syndrome