Comparative efficacy of uncontrolled and controlled intermittent preventive treatment during pregnancy (IPTp) with combined use of LLTNs in high resistance area to sulfadoxine-pyrimethamine in C&ocirc;te d&rsquo;Ivoire | Zendy

Andre Offianan | Zendy; Penali | Zendy; Coulibaly Coulibaly | Zendy; N'Guessan | Zendy; Ako | Zendy; Adji | Zendy; David Koffi | Zendy; Sarr | Zendy; Jambou | Zendy; Koné | Zendy

Open Access

Comparative efficacy of uncontrolled and controlled intermittent preventive treatment during pregnancy (IPTp) with combined use of LLTNs in high resistance area to sulfadoxine-pyrimethamine in Côte d’Ivoire

Author(s) -

Andre Offianan,

Penali,

Coulibaly Coulibaly,

N'Guessan,

Ako,

Adji,

David Koffi,

Sarr,

Jambou,

Koné

Publication year - 2012

Publication title -

infection and drug resistance

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.033

H-Index - 39

ISSN - 1178-6973

DOI - 10.2147/idr.s27450

Subject(s) - sulfadoxine/pyrimethamine , sulfadoxine , medicine , pregnancy , pyrimethamine , pharmacology , obstetrics , malaria , immunology , biology , chloroquine , genetics

In recent years, intermittent preventive treatment for pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) has become policy in much of sub-Saharan Africa. But resistance to SP has been spreading across sub-Saharan Africa and thus the effectiveness of IPTp-SP has been questioned. The present study therefore sought to assess the incidence of placental malaria, low birth weight, and anemia of two IPTp-SP approaches (directly observed treatment scheme versus no directly observed treatment) in Anonkoua-Kouté and Samo, Côte d'Ivoire where the reported prevalence of dfr single mutant 108 was 62% and 52.2%, respectively.

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