Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance | Zendy

Liming Chen | Zendy; Deverick J. Anderson | Zendy; David L. Paterson | Zendy

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Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance

Author(s) -

Liming Chen,

Deverick J. Anderson,

David L. Paterson

Publication year - 2012

Publication title -

infection and drug resistance

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.033

H-Index - 39

ISSN - 1178-6973

DOI - 10.2147/idr.s26613

Subject(s) - klebsiella pneumoniae , epidemiology , beta lactam , drug resistance , microbiology and biotechnology , klebsiella infections , multi drug resistant , medicine , resistance (ecology) , intensive care medicine , biology , antibiotics , escherichia coli , gene , genetics , ecology

Klebsiella pneumoniae carbapenemases (KPCs) confer resistance to nearly all β-lactams. This broad-spectrum drug resistance mechanism has rapidly spread in the United States and is reportedly increasing elsewhere in the world. Thus, the emergence of KPC resistance is a major threat to global health. This article reviews the epidemiology and provides an overview of the dissemination of KPC-producing organisms.

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