<p>Successful management of <em>Mycobacterium abscessus</em> complex lung disease in an otherwise healthy infant</p>
Author(s) -
Hui Liu,
Fang Dong,
Jinrong Liu,
Jianhua Liu,
Yu Pang,
Shunying Zhao,
Jie Lu,
Huimin Li
Publication year - 2019
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s198461
Subject(s) - mycobacterium abscessus , medicine , lung disease , lung , disease , mycobacterium , pathology , tuberculosis
Mycobacterium abscessus complex (MABC) is an uncommon but increasingly important cause of invasive pulmonary disease, a condition associated with diagnostic and management challenges. MABC has mainly been reported in children with certain medical conditions, such as preexisting structural lung disorders and immunocompromised status. In this article, we describe a rare case of MABC pulmonary disease in an otherwise healthy infant. A 4-month-old female presented with cough and fever for 4 days. Computed tomography showed multiple masses and small nodules across both lungs. Isolated mycobacteria from her bronchoalveolar lavage fluid and gastric aspirate were identified as MABC by using matrix-assisted laser desorption ionization time-of-flight mass spectrometry and M. abscessus subsp. massiliense was ultimately identified by DNA sequence analysis. Prolonged treatment with a combination of azithromycin, cefoxitin, and moxifloxacin achieved a successful treatment outcome.
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