Open AccessEfficacy and safety of prolonged-release melatonin for insomnia in middle-aged and elderly patients with hypertension: a combined analysis of controlled clinical trials
Author(s) -
Am Katz,
Lemoine,
Wade,
Nir,
Zisapel
Publication year - 2012
Publication title -
integrated blood pressure control
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 20
ISSN - 1178-7104
DOI - 10.2147/ibpc.s27240
Subject(s) - medicine , placebo , insomnia , adverse effect , clinical trial , sleep disorder , pharmacology , alternative medicine , pathology
Add-on prolonged-release melatonin (PRM) in antihypertensive therapy has been shown to ameliorate nocturnal hypertension. Hypertension is a major comorbidity among insomnia patients. The efficacy and safety of PRM for primary insomnia in patients aged 55 years and older who are treated with antihypertensive drugs were evaluated.
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