Diet-induced metabolic hamster model of nonalcoholic fatty liver disease | Zendy

Satya Prakash | Zendy; Jasmine Bhathena | Zendy; A Urbańska | Zendy; Arun Kulamarva | Zendy; Meenakshi Malhotra | Zendy; Christopher Martoni | Zendy; Arghya Paul | Zendy

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Diet-induced metabolic hamster model of nonalcoholic fatty liver disease

Author(s) -

Satya Prakash,

Jasmine Bhathena,

A Urbańska,

Arun Kulamarva,

Meenakshi Malhotra,

Christopher Martoni,

Arghya Paul

Publication year - 2011

Publication title -

diabetes metabolic syndrome and obesity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.853

H-Index - 43

ISSN - 1178-7007

DOI - 10.2147/dmso.s18435

Subject(s) - endocrinology , medicine , nonalcoholic fatty liver disease , fatty liver , metabolic syndrome , dyslipidemia , cholesterol , hyperlipidemia , biology , obesity , diabetes mellitus , disease

Obesity, hypercholesterolemia, elevated triglycerides, and type 2 diabetes are major risk factors for metabolic syndrome. Hamsters, unlike rats or mice, respond well to diet-induced obesity, increase body mass and adiposity on group housing, and increase food intake due to social confrontation-induced stress. They have a cardiovascular and hepatic system similar to that of humans, and can thus be a useful model for human pathophysiology.

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