Open AccessIn vitro and in vivo evaluation of a sublingual fentanyl wafer formulation
Author(s) -
Stephen Lim,
M. J. Paech,
Sunderland,
Liu
Publication year - 2013
Publication title -
drug design development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s42619
Subject(s) - fentanyl , bioavailability , ivivc , materials science , wafer , chromatography , in vivo , chemistry , pharmacology , biomedical engineering , dissolution testing , medicine , nanotechnology , microbiology and biotechnology , biology , biopharmaceutics classification system
The objective of this study was to prepare a novel fentanyl wafer formulation by a freeze-drying method, and to evaluate its in vitro and in vivo release characteristics, including its bioavailability via the sublingual route.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom