<p>Ginkgolide B ameliorates myocardial ischemia reperfusion injury in rats via inhibiting endoplasmic reticulum stress</p>
Author(s) -
Changlei Guo,
Junbiao Zhang,
Peiyong Zhang,
Aoyang Si,
Zhenling Zhang,
Liangping Zhao,
Fenghua Lv,
Guoan Zhao
Publication year - 2019
Publication title -
drug design development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s179101
Subject(s) - endoplasmic reticulum , unfolded protein response , tunel assay , lactate dehydrogenase , reperfusion injury , pi3k/akt/mtor pathway , protein kinase b , medicine , atf6 , pharmacology , chemistry , troponin i , terminal deoxynucleotidyl transferase , western blot , endocrinology , apoptosis , ischemia , myocardial infarction , biochemistry , enzyme , gene
Ginkgolide B (GB) is a terpene lactone component found in Ginkgo biloba , which has a protective role on ischemia reperfusion (I/R) injury. This study was aimed at exploring the protective mechanism of GB on the myocardial I/R.
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