Managing insulin resistance: role of liraglutide | Zendy

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Managing insulin resistance: role of liraglutide

Author(s) -

Sharma

Publication year - 2010

Publication title -

clinical pharmacology advances and applications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.685

H-Index - 27

ISSN - 1179-1438

DOI - 10.2147/cpaa.s10496

Subject(s) - liraglutide , insulin resistance , dyslipidemia , medicine , diabetes mellitus , insulin , glycemic , endocrinology , type 2 diabetes

Diabetes mellitus is part of the insulin resistance syndrome, which includes hypertension, dyslipidemia, and obesity as its other components. Conversely, insulin resistance is a major pathophysiologic factor in the development of type 2 diabetes. It makes sense, therefore, to choose an anti-diabetic medication that acts on insulin resistance and its clinical components, while having anti-hyperglycemic effects as well. This review discusses the non-glycemic, or extra-pancreatic effects, including insulin sensitization, of liraglutide, a novel GLP-1 analog.

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