Open AccessSuppressive activity of tiotropium bromide on matrix metalloproteinase production from lung fibroblasts in vitro
Author(s) -
Kazuhito Asano
Publication year - 2008
Publication title -
international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s3945
Subject(s) - matrix metalloproteinase , medicine , stimulation , tumor necrosis factor alpha , copd , lung , pathogenesis , endocrinology , inflammation
Chronic obstructive pulmonary disease (COPD) is characterized by airway remodeling with an accumulation of inflammatory cells. There is also increasing evidence that metalloproteinases (MMPs) may contribute to the pathogenesis of COPD, but the influence of agents that used for the treatment of COPD is not well understood.
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