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The safety of long-acting ß2-agonists in the treatment of stable chronic obstructive pulmonary disease
Author(s) -
M. Decramer,
Hanania,
Jan Lötvall,
Barbara P. Yawn
Publication year - 2013
Publication title -
international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s39018
Subject(s) - indacaterol , medicine , formoterol , copd , salmeterol , tolerability , adverse effect , placebo , exacerbation , bronchodilator , anesthesia , intensive care medicine , asthma , budesonide , alternative medicine , pathology
Inhaled long-acting bronchodilators are the mainstay of pharmacotherapy for chronic obstructive pulmonary disease (COPD). Both the twice-daily long-acting β(2)-adrenoceptor agonists (LABAs) salmeterol and formoterol and the once-daily LABA indacaterol are indicated for use in COPD. This review examines current evidence for the safety of LABAs in COPD, focusing on their effect on exacerbations and deaths.

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