High pressure versus high intensity noninvasive ventilation in stable hypercapnic chronic obstructive pulmonary disease: a randomized crossover trial | Zendy

Patrick B. Murphy | Zendy; Brignall | Zendy; Moxham | Zendy; Michael I. Polkey | Zendy; Davidson | Zendy; Nicholas Hart | Zendy

Open Access

High pressure versus high intensity noninvasive ventilation in stable hypercapnic chronic obstructive pulmonary disease: a randomized crossover trial

Author(s) -

Patrick B. Murphy,

Brignall,

Moxham,

Michael I. Polkey,

Davidson,

Nicholas Hart

Publication year - 2012

Publication title -

international journal of copd

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 67

eISSN - 1178-2005

pISSN - 1176-9106

DOI - 10.2147/copd.s36151

Subject(s) - medicine , copd , crossover study , anesthesia , vital capacity , ventilation (architecture) , cardiology , physical therapy , lung , placebo , lung function , mechanical engineering , alternative medicine , pathology , diffusing capacity , engineering

High-intensity (high-pressure and high backup rate) noninvasive ventilation has recently been advocated for the management of stable hypercapnic chronic obstructive pulmonary disease (COPD). However, the relative contributions of high inspiratory pressure and high backup rate to ventilator adherence and physiological outcome have not been investigated.

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