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Suppression of IL-8 production from airway cells by tiotropium bromide in vitro
Author(s) -
Kazuhito Asano,
Isao Suzaki,
Yusuke Shikama,
Taisuke Hamasaki,
Ayako Kanei,
Harumi Suzaki
Publication year - 2011
Publication title -
international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s23695
Subject(s) - medicine , tiotropium bromide , in vitro , airway , interleukin 8 , immunology , cytokine , lung function , lung , anesthesia , biochemistry , chemistry
COPD is characterized by persistent and progressive airway inflammation. Although neutrophilic airway inflammation is generally accepted to be a major factor in the pathogenesis of COPD, the influence of the agents used for the treatment of COPD on neutrophil functions such as chemotaxis is not fully understood.

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