Haemophilus influenzae and smoking-related obstructive airways disease
Author(s) -
Cripps,
Otczyk,
Clancy
Publication year - 2011
Publication title -
international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s19359
Subject(s) - medicine , haemophilus influenzae , copd , pulmonary disease , microbiology and biotechnology , intensive care medicine , environmental health , antibiotics , biology
Intralumenal bacteria play a critical role in the pathogenesis of acute infective episodes and airway inflammation. Antigens from colonizing bacteria such as nontypeable Haemophilus influenzae (NTHi) may contribute to chronic lung disease through an immediate hypersensitivity response. The objective of this study was to determine the presence of specific NTHi-IgE antibodies in subjects with chronic bronchitis (CB) and COPD who had smoked.
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