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<p>MiR-935 Promotes Clear Cell Renal Cell Carcinoma Migration and Invasion by Targeting IREB2</p>
Author(s) -
Fei Liu,
Yuedong Chen,
Bin Chen,
Chunxiao Liu,
Jinchun Xing
Publication year - 2019
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s232380
Subject(s) - clear cell renal cell carcinoma , gene silencing , cancer research , cell migration , cell growth , oncogene , metastasis , cancer , microrna , cell , biology , renal cell carcinoma , cell cycle , medicine , pathology , biochemistry , genetics , gene
Clear cell renal cell carcinoma (ccRCC) has the highest rate of metastasis and invasion in RCC and is the third most common adult urinary malignancy. miRNA may serve a critical role in human cancer development and progression, has been confirmed to play a pivotal role in RCC cell invasion and migration. Since miR‑935 had been verified to be an oncogene or tumor suppressor in various cancers, the role of miR‑935 in RCC was unclear.

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