Open AccessDownregulation of PIM1 regulates glycolysis and suppresses tumor progression in gallbladder cancer
Author(s) -
Chen Xue,
Yuting He,
Qiuyue Hu,
Yan Yu,
Xiaolong Chen,
Jianan Chen,
Fang Ren,
Juan Li,
Zhigang Ren,
Guangying Cui,
Ranran Sun
Publication year - 2018
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s184381
Subject(s) - pim1 , cancer research , biology , cell cycle , oncogene , cell growth , anaerobic glycolysis , apoptosis , glycolysis , chemistry , microbiology and biotechnology , biochemistry , serine , phosphorylation , enzyme
PIM1, a serine/threonine kinase, plays an essential role in tumorigenesis of multiple types of tumors. However, the expression pattern and functions of PIM1 in gallbladder cancer (GBC) remain largely unknown.
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