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Long noncoding RNA SNHG6 functions as a competing endogenous RNA by sponging miR-181a-5p to regulate E2F5 expression in colorectal cancer
Author(s) -
Yu Chen,
Sun Jun-xi,
Xiaogang Leng,
Jianxiu Yang
Publication year - 2019
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s182719
Subject(s) - biology , gene knockdown , colorectal cancer , long non coding rna , cell growth , cancer research , rna interference , competing endogenous rna , downregulation and upregulation , metastasis , cancer , cell , cell culture , rna , gene , genetics
Long noncoding RNAs (lncRNAs) have been identified as a novel class of regulators implicated in diverse biological processes in human cancers. Currently, evidence have shown that SNHG6, a cancer-associated lncRNA, exerts critical functions in gastric cancer and hepatocellular carcinoma; however, its role in colorectal cancer (CRC) remains unclear.

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