Overexpression of chloride channel-3 predicts unfavorable prognosis and promotes cellular invasion in gastric cancer
Author(s) -
Jianjun Peng,
Wei Chen,
Jianhui Chen,
Yujie Yuan,
Jian Zhang,
Yulong He
Publication year - 2018
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s159790
Subject(s) - cancer , cancer research , gene silencing , cancer cell , immunohistochemistry , western blot , chloride channel , gentamicin protection assay , smad , cell growth , in vitro , apoptosis , biology , medicine , pathology , transforming growth factor , microbiology and biotechnology , metastasis , biochemistry , gene
Chloride channel-3 (CLC-3) has been reported to promote the proliferation and invasion in various tumors, yet little is known about its role in gastric cancer. In the present study, we investigated the clinical significance of CLC-3 and its biological role in gastric cancer.
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