Inhibition of SIRT1 combined with gemcitabine therapy for pancreatic carcinoma
Author(s) -
Guo,
Daojun Gong,
Jiamin Zhang,
Min Yu,
B. A. Zhuang
Publication year - 2013
Publication title -
clinical interventions in aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 76
eISSN - 1178-1998
pISSN - 1176-9092
DOI - 10.2147/cia.s45064
Subject(s) - gemcitabine , medicine , pancreatic cancer , combination therapy , in vivo , oncology , antimetabolite , cancer research , pharmacology , chemotherapy , cancer , biology , microbiology and biotechnology
Pancreatic carcinoma possesses one of the highest lethality rates, highest drug-resistance, and highest incidence rates. The objective of this research was to enhance the efficacy and drug-resistance for pancreatic carcinoma by using inhibition of SIRT1 combined with gemcitabine therapy methods.
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