Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflammation and immune response mediators in tears from patients with dry eye disorders
Author(s) -
M.D. Pinazo-Durán,
Carmen Galbis-Estrada,
Pons-Vázquez,
Jorge Cantu-Dibildox,
Carla Marco-Ramírez,
Javier Benítez del Castillo Sánchez
Publication year - 2013
Publication title -
clinical interventions in aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 76
eISSN - 1178-1998
pISSN - 1176-9092
DOI - 10.2147/cia.s40640
Subject(s) - medicine , inflammation , interleukin 8 , tears , polyunsaturated fatty acid , pathogenesis , interleukin 10 , interleukin , immune system , calprotectin , immunology , gastroenterology , cytokine , fatty acid , biochemistry , disease , chemistry , inflammatory bowel disease
Women, and those older than 65 years of age, are particularly susceptible to dry eye disorders (DEDs). Inflammation is clearly involved in the pathogenesis of DEDs, and there is mounting evidence on the antioxidant and antiinflammatory properties of essential polyunsaturated fatty acids (EPUFAs).
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