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Carvedilol in the treatment of elderly patients with chronic heart failure
Author(s) -
Klaus K. Witte
Publication year - 2008
Publication title -
clinical interventions in aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 76
eISSN - 1178-1998
pISSN - 1176-9092
DOI - 10.2147/cia.s1044
Subject(s) - medicine , carvedilol , heart failure , blockade , incidence (geometry) , cardiology , adrenergic , randomized controlled trial , intensive care medicine , physics , receptor , optics
Chronic heart failure (CHF) is common, and increases in incidence and prevalence with age. There are compelling data demonstrating reduced mortality and hospitalizations with adrenergic blockade in older patients with CHF. Despite this, many older patients remain undertreated. The aim of the present article is to review the potential mechanisms of the benefits of adrenergic blockade in CHF and the clinical data available from the large randomized studies, focusing particularly on older patients.

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