Cost-effectiveness analysis of intravenous levetiracetam versus intravenous phenytoin for early onset seizure prophylaxis after neurosurgery and traumatic brain injury | Zendy

Mark Bounthavong | Zendy; Rashid Kazerooni | Zendy

Open Access

Cost-effectiveness analysis of intravenous levetiracetam versus intravenous phenytoin for early onset seizure prophylaxis after neurosurgery and traumatic brain injury

Author(s) -

Mark Bounthavong,

Rashid Kazerooni

Publication year - 2010

Publication title -

clinicoeconomics and outcomes research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.591

H-Index - 27

ISSN - 1178-6981

DOI - 10.2147/ceor.s8965

Subject(s) - levetiracetam , medicine , phenytoin , anesthesia , neurosurgery , discontinuation , epilepsy , adverse effect , pharmacology , surgery , psychiatry

There has been growing interest in newer anti-epileptic drugs (AEDs) for seizure prophylaxis in the intensive care setting because of safety and monitoring issues associated with conventional AEDs like phenytoin. This analysis assessed the cost-effectiveness of levetiracetam versus phenytoin for early onset seizure prophylaxis after neurosurgery and traumatic brain injury (TBI).

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