Emerging treatment options for short bowel syndrome: potential role of teduglutide
Author(s) -
Tee,
Gabe,
Katharina Wallis
Publication year - 2011
Publication title -
clinical and experimental gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.113
H-Index - 30
ISSN - 1178-7023
DOI - 10.2147/ceg.s13906
Subject(s) - medicine , short bowel syndrome , intensive care medicine , parenteral nutrition
Current medical management of short bowel syndrome (SBS) involves the use of lifelong parenteral nutrition (PN). Glucagon-like peptide-2 (GLP-2), an important intestinotrophic growth factor has been shown to increase intestinal absorption in SBS through augmentation of post-resection intestinal adaptation. This may lead to the reduction of PN dependence in patients with SBS.
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