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Fosaprepitant and aprepitant: an update of the evidence for their place in the prevention of chemotherapy-induced nausea and vomiting
Author(s) -
Patrick Langford
Publication year - 2010
Publication title -
core evidence
Language(s) - English
Resource type - Journals
eISSN - 1555-175X
pISSN - 1555-1741
DOI - 10.2147/ce.s6012
Subject(s) - aprepitant , medicine , chemotherapy induced nausea and vomiting , nausea , vomiting , ondansetron , chemotherapy , oncology , anesthesia , antiemetic
The selective neurokinin-1 receptor antagonist aprepitant is effective in the treatment of acute and delayed chemotherapy-induced nausea and vomiting (CINV) associated with both moderately and highly emetogenic chemotherapy. Fosaprepitant has been developed as an intravenous prodrug of aprepitant.

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