Dermal benefits of topical D-ribose | Zendy

John St. Cyr | Zendy

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Dermal benefits of topical D-ribose

Author(s) -

John St. Cyr

Publication year - 2009

Publication title -

clinical cosmetic and investigational dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.73

H-Index - 35

ISSN - 1178-7015

DOI - 10.2147/ccid.s7487

Subject(s) - wrinkle , skin aging , ribose , microbiology and biotechnology , chemistry , biochemistry , medicine , biology , dermatology , gerontology , enzyme

Our aging skin undergoes changes with reductions in collagenous and elastic fibers, fibroblasts, mast cells, and macrophages with free radical production, which can result in reduced skin tone and wrinkle formation. Fibroblasts are important for dermal integrity and function with a decrease in function producing less skin tone, thinning, and wrinkle formation. Dermal levels of adenosine triphosphate (ATP) decline with aging, potentially altering dermal function. Supplemental D-ribose, a natural occurring carbohydrate, enhances ATP regeneration. D-ribose-based studies demonstrated benefits in both cell culture fibroblastic activities and a subsequent clinical study in women with decreased skin tone with wrinkles. Supplemental D-ribose may offer this needed cellular benefit.

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