Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebo-controlled, double-blind study
Author(s) -
Daniela Buonocore,
Nobile,
Cestone,
Santin,
Bottone,
Marzatico,
Lazzeretti,
Tocabens
Publication year - 2012
Publication title -
clinical cosmetic and investigational dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 35
ISSN - 1178-7015
DOI - 10.2147/ccid.s36102
Subject(s) - nutraceutical , resveratrol , medicine , proanthocyanidin , placebo , pharmacology , traditional medicine , polyphenol , antioxidant , biochemistry , alternative medicine , chemistry , pathology
Skin is constantly exposed to pro-oxidant environmental stress from several sources, including air pollutants, ultraviolet solar light, and chemical oxidants. Reactive oxygen species have been implicated in age-related skin disorders. Dietary bioactive antioxidant compounds, such as polyphenols, have beneficial effects on skin health. The advantage of a nutritional administration route is that blood delivers nutraceutical bioactive compounds continuously to all skin compartments, ie, the epidermis, dermis, and subcutaneous fat. The purpose of this study was to evaluate the topical and systemic effects of a dietary supplement containing resveratrol and procyanidin on age-related alterations to the skin, the skin antioxidant pool, and systemic oxidative stress levels.
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